PRP vs. PRF: What's the Difference in Skin & Hair Regeneration?

Ever feel like you're drowning in alphabet soup when exploring advanced skincare? PRP, PRF, micro needling, exosomes, it’s enough to make your head spin (and maybe your skin break out).

Let’s simplify.

Both PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are powerful regenerative treatments that use your own blood to heal, restore, and rejuvenate. But they’re not interchangeable, and one may suit your skin or hair goals better than the other.

What is PRP?

• Your blood is spun to isolate a high concentration of platelets

• Delivers a quick, potent boost of growth factors

• Often paired with microneedling, hair restoration, or facial rejuvenation

  
  

What is PRF?

• Uses less spin = more natural cellular components preserved

• Releases growth factors gradually = longer-lasting effects

• Contains white blood cells and fibrin = supports deeper healing

• Can be transformed into PRF Gel—a natural dermal filler that stimulates collagen and enhances volume

  
  

Which One Should You Choose?

• Choose PRP if you want faster results, especially for hair loss or visible texture concerns

• Choose PRF for a gentler, longer-lasting rejuvenation with fewer additives

• Ask about PRF Gel if you’re interested in a more natural filler alternative

  
  

What We Do at Refresh LKN

You’re not a barcode, you’re a face we want to see glow. We don’t guess. We guide.

Whether it’s PRP, PRF, or PRF Gel, your treatment is personalized based on your skin, your goals, and your lifestyle.

Our founder, Josette M. Giuffrida, DNP, FNP-C, combines medical expertise with an artist’s eye, ensuring subtle, stunning results every time.